Find Tuberculosis
LTS is excited to announce a groundbreaking rapid point-of-care test for Active TB.
About Tuberculosis
Tuberculosis (TB) is a global disease, found in every country in the world. It is one of the leading infectious causes of death worldwide and the Coronavirus pandemic has resulted in an increase of cases.
The World Health Organization estimates that 1.8 billion people—close to one quarter of the world's population—are infected with Mycobacterium tuberculosis (M.tb), the bacteria that causes TB. According to the WHO, 10.6 million people were diagnosed with TB in 2021, a 4.5% increase on the previous year. TB is an airborne disease that can be spread by coughing or sneezing and is the leading cause of infectious disease worldwide. It is responsible for economic devastation and the cycle of poverty and illness that entraps families, communities and even entire countries. Among the most vulnerable are women, children, and those with HIV/AIDS. There is growing resistance to available drugs, which means the disease is becoming more deadly and difficult to treat. There were more than half a million cases of drug resistant TB in 2020.
Source: TB Alliance
What is TB?
Tuberculosis, or TB, is a bacterial infection that can spread through the air. It is most often found in the lungs, but can exist in any organ in your body. When a person coughs or sneezes, they can transmit so-called “active” TB.
However, many people are also infected with an inactive form of TB, known as latent TB. The bacillus that causes the disease is called Mycobacterium tuberculosis (M.tb).M.tb's unique cell wall, which has a waxy coating primarily composed of mycolic acids, allows the bacillus to lie dormant for many years. The body's immune system may restrain the disease, but it does not destroy it. While some people with this latent infection will never develop active TB, five to 10 percent of carriers will become sick in their lifetime.
From the page: https://www.tballiance.org/why-new-tb-drugs/global-pandemic
Our Test
Find™ TB is a Point-of-care rapid test card intended to detect circulating antibodies against three antigens in whole blood samples, present in the active stage of infection by M tuberculosis.
Find™ TB is intended to be used by first-contact providers in decentralised healthcare facilities to rule out Tuberculosis (triage-test negative) and direct positive individuals for further evaluation.
Find™ TB is based on the agglutination of antibodies in whole blood samples with recombinant VNAR proteins on a paper microfluidic device. The result of the test is evaluated by image processing with the Xplora™ smartphone app using artificial intelligence algorithms. Test results are shown in the app and sent in real time to a cloud server for result reporting and data analytics.
Who can this test help?
Governments
Public Health Authorities including hospitals, clinics and military procurement
Humanitarian refugee organisations, Transport hubs for immigration purposes in both high TB burden and non high TB burden countries
Life Testing Solutions believes low cost rapid point of care testing will enable mass screening for Active TB in order to help the global fight against the spread of the disease.
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